January 9, 2025
Article

Balancing Act: How Physical Activity Intensity and Volume Influence Lifespan

Engaging in regular physical activity is widely recognized as a cornerstone of a healthy lifestyle, but the optimal balance between the intensity and volume of exercise for promoting longevity has been a topic of ongoing research. Recent findings suggest that both the vigor (intensity) and the total amount (volume) of physical activity play crucial roles in extending lifespan. High-intensity exercises, such as running or vigorous sports, can enhance cardiovascular health and boost metabolic functions, while moderate activities like walking or gardening contribute to overall well-being and are more sustainable over the long term.

The interplay between intensity and volume is complex. Incorporating a mix of moderate and vigorous activities into one's routine may offer the most significant benefits for longevity. This combination allows individuals to reap the advantages of high-intensity workouts without overexertion, reducing the risk of injury and promoting consistent exercise habits. Importantly, even low-intensity activities contribute positively, especially for those who may be unable to engage in more strenuous exercises due to health constraints.

Understanding terms like 'cardiovascular health'—which refers to the health of the heart and blood vessels—and 'metabolic functions'—the processes by which our bodies convert food into energy—can help individuals make informed decisions about their exercise routines. By tailoring physical activity to include both intensity and volume suited to personal health status and preferences, individuals can enhance their chances of living longer, healthier lives.

Article Information

Intensity or volume: the role of physical activity in longevity

Published in the European Journal of Preventive Cardiology. Schwendinger F. et al.

Abstract

Aims: To investigate how physical activity (PA) volume, intensity, duration, and fragmentation are associated with the risk of all-cause and cardiovascular disease mortality. To produce centile curves for PA volume and intensity representative of US adults.

Methods and results: This study is based on the observational 2011-2014 National Health and Nutrition Examination Survey (NHANES). Adults (age, ≥20) with valid accelerometer, covariate, and mortality data were included. Average acceleration (AvAcc), intensity gradient (IG), and total PA served as proxies for volume, intensity, and duration of PA, respectively. Weighted Cox proportional hazard models estimated associations between outcome and PA metrics. In 7518 participants (52.0% women, weighted median age of 49), there were curvilinear inverse dose-response relationships of all-cause mortality risk (81-month follow-up) with both AvAcc [-14.4% (95% CI, -8.3 to -20.1%) risk reduction from 25th to 50th percentile] and IG [-37.1% (95% CI, -30.0 to -43.4%) risk reduction from 25th to 50th percentile], but for cardiovascular disease (CVD) mortality risk (n = 7016, 82-month follow-up) only with IG [-41.0% (95% CI, -26.7 to -52.4%) risk reduction from the 25th to 50th percentile]. These relationships plateau at AvAcc: ∼35-45 mg and IG: -2.7 to -2.5. Associations of PA with all-cause and cardiovascular disease mortality are primarily driven by intensity and secondary by volume. Centile curves for volume and intensity were generated.

Conclusion: Intensity is a main driver of reduced mortality risk suggesting that the intensity of PA rather than the quantity matters for longevity. The centile curves offer guidance for achieving desirable PA levels for longevity.